![]() ![]() Increasing age was inversely associated with LAaf (β = −1.93, p < 0.001). In regression analysis, hypertension was significantly associated with larger gated LA max (β = 1.30), LA min (β = 1.07), and non-gated NGLA (β = 0.94, all p ≤ 0.037). The measurements were highly reproducible (all intraclass correlation coefficients ≥ 0.98). Results: Data from 378 subjects were included in the analysis (mean age: 56.3 years, 57.7 % male). ![]() Linear regression analyses were conducted to link LA size and function with cardiovascular risk factors. ![]() Inter-and intra-reader reliability tests were performed ( n = 31). The area-based LA function was defined as LAaf = (LA max − LA min)/LA max. The LA maximum and minimum sizes were segmented in gated CINE four-chamber sequences (LA max and LA min) and non-gated T1 VIBE-Dixon (NGLA). Methods: 3-Tesla MRIs were performed on 400 subjects enrolled in the KORA (Cooperative Health Research in the Augsburg Region) MRI study. Background: In magnetic resonance imaging (MRI), the comparability of gated and non-gated measurements of the left atrial (LA) area and function and their association with cardiovascular risk factors have not been firmly established.
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